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Studies have shown that the expression of SLC7A11 is regulated by multiple mechanisms, including transcription, epigenetics, and post-translational modification [33,34,35]

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Secondly, it was found that dietary Se intake was weakly correlated with peripheral Se levels such as whole blood and serum (84), and the intake of Se did not accurately reflect the relationship of serum Se and thyroid carcinoma, which may be another reason for the inconsistent results of this experiment