The review also covered three therapeutic research strategies: direct GSH depletion (leading to ferroptosis or enhanced chemotherapy sensitivity), indirect approaches targeting the tumour microenvironment, and prodrug strategies utilising elevated tumour GSH for drug activation
Mitochondrial dual protection : Hydrogen's direct access to mitochondria complements the actions of manganese (as SOD2) and selenium (as GPx1) in protecting these critical energy-producing organelles from their high endogenous free radical production
Food Sci Nutr 13(1):e4706 Javed MN, Dahiya ES, Ibrahim AM, Alam MS, Khan FA, Pottoo FH (2020) Recent advancement in clinical application of nanotechnological approached targeted delivery of herbal drugs
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(2022) reported that DMSO was observed to increase the expression of Nrf2
