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ER stress and ER stress-mediated apoptosis are involved in manganese-induced neurotoxicity in the rat striatum in vivo

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Cytosolic GSH crosses the mitochondrial outer membrane (MOM) through rapid porin-mediated exchange (Figure 1) and is then transported into the matrix primarily through inner mitochondria membrane (IMM) proteins of the SLC25 family: the dicarboxylate carrier (DIC) and the 2-oxoglutarate carrier (OGC) [36]

In contrast VV9-7P and VV9-7W displayed no KIR2DS4-Fc binding (Fig