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In PD, the spread of the pathological alpha-synuclein from the gut to the brain is mediated along the vagus nerve

Oct 5 2020;25(19)doi:10.3390/molecules25194554 Shojaei-Zarghani S, Rafraf M

This deficiency kicks up heart and lung problems, putting you right in the path of danger

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8.1.2 Before initiating second-line immunosuppressive therapy, it is essential to exclude sub-optimal dosing, non-adherence, alternative etiologies, co-morbidities and autoimmune sclerosing cholangitis/overlap syndrome (LOE 5, Strong recommendation)