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In addition, some researchers reported that the increased serum UA may lower the pH in the oral cavity or periodontal pocket, which could promote the growth and the reproduction of acid-producing periodontopathogens like Prevotella and may increase the incidence of periodontitis (93)

In fact, H 2 O 2 plays the role of a second messenger in some pathways that involve the transduction of extracellular signals and the control of gene expression, contributing to what is currently defined as redox signaling 1

Historically, the distinctions between these degenerative diseases have been emphasized

Functional capacity for daily activities

After eight weeks, there was no trace of cellular and nuclear atypia and abnormal proliferation