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10.1093/humupd/dmae023 90 WangR.LiX.XuY.LiY.ZhangW.GuoR.et al (2024)

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today Since its discovery in the 1980s, GHK-Cu has attracted scientists' attention due to its remarkable ability to rejuvenate the skin and accelerate the regeneration of damaged tissues

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For example, increased oxidative stress in the nematode Caenorhabditis elegans does not necessarily shorten lifespan and may even activate the Krppel-like factor-1 (KLF-1) transcription factor, which alters mitochondrial function to extend lifespan [261, 262]

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Mol Biol Cell 8:16991707 Hara KY, Aoki N, Kobayashi J, Kiriyama K, Nishida K, Araki M, Kondo A (2015) Improvement of oxidized glutathione fermentation by thiol redox metabolism engineering in Saccharomyces cerevisiae

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