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That reality excluded patients who couldnt or wouldnt self-inject, regardless of how much they might have benefited from treatment

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Contraindications & Precautions Hypersensitivity to methylcobalamin Caution in patients with kidney or liver disorders Use during pregnancy and lactation only if prescribed Who should not take methylcobalamin injection

Contemporary professional societies recommend reserving liothyronine for specific indications or for patients who do not achieve euthyroid symptom resolution on levothyroxine monotherapy, reinforcing its status as a prescription-only, physician-monitored therapy