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In a study participants who were treated with semaglutide (the active ingredient in Wegovy) reported a significant reduction in appetite, which contributed to an average weight loss of 14.9% of body weight over 68 weeks
Its unlikely that the observed lean mass loss represents a serious adverse effect, says Takuya Karasawa, PhD, postdoctoral researcher in the U of U Molecular Medicine Program and co-first author on the study
A study investigating surgery in parallel with adalimumab treatment in HS reported that adalimumab was efficacious in conjunction with wide-excision surgery, with no increased risk of postoperative wound infection, indicating no requirements for interrupting biologic treatment prior to surgery (71)
Its important to avoid activities that require alertness, such as driving, until you know how the combination of these drugs affects you