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Of the total increase in risk, about 10% of that excess risk was estimated to be due to TMAO-related metabolites

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J Clin Endocrinol Metab (1992) 74(1):6470

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It is worth noting that there are distinctions between capillary-associated and parenchymal microglia, however, parenchymal microglia can transition to capillary-associated microglia (Bisht et al., 2021)