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The morphology of mitochondria was studied by transmission electron microscopy (TEM) using a Hitachi TEM system (HT7800, Tokyo, Japan)

FDA adverse event data (as of early 2025) 455+ adverse event reports linked to compounded semaglutide 320+ adverse event reports linked to compounded tirzepatide Many involved dosing errors from multidose vials, some requiring hospitalization Reports include severe nausea, vomiting, dehydration, and overdose symptoms Documented contamination, mislabeling, and counterfeit product cases 1

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Never discontinue GLP-1 medication without consulting your prescriber, as abrupt cessation may affect glycaemic control or weight management progress

doi: 10.1016/j.cpha.2020.08.004