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4.3 Obstructive sleep apnea OSA is a common sleep-related breathing disorder characterized by recurrent airway collapse during sleep, leading to intermittent hypoxia and systemic oxidative stress, which induce chronic inflammation and affect nearly one billion adults worldwide (77).OSA and periodontitis share multiple common risk factors, including age, smoking, alcohol consumption, DM, and obesity, indicating a potential association between the two conditions (78)

Barreiro E, de la Puente B, Busquets S, Lpez-Soriano FJ, Gea J, Argils JM

It is a peptide, which is a sequence of 15 amino acids

L-carnitine, n = 20)

Selank inhibits the enzymes that break down enkephalins, which are ligands for opioid receptors