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BMS-754807 is a potent IGF-1R inhibitor, which has been reported to have a limited off-target effect since the transcriptional profile is similar between wild-type MEF cells treated with BMS-754807 and IGF-1R null MEF cells

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Published veterinary research on the peptide contributed to understanding of its mechanisms and safety profile, though this animal data has not been directly replicated in human clinical trials

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