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Current treatments are largely palliative and do not address the underlying fibrosis

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The distinct response to aspirin of these two strains, described in past studies carried out in our laboratory 18,19,20 , was indeed again made immediately apparent in our transcriptome analysis, which showed that aspirin altered the gene expression profile of EG110 cells to a greater and significantly different extent than that of EG103 cells (Figs 13)