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Comparative efficacy of bariatric surgery in the treatment of morbid obesity and diabetes mellitus: a systematic review and network meta-analysis

USD 39.95 Prices may be subject to local taxes which are calculated during checkout Similar content being viewed by others Data availability This meta-analysis is based on data extracted from previously published research that belongs to the public domain

After 24 hours of incubation at 37C, colony counts were performed to quantify surviving bacteria

Notably, mutating the nuclear localization signal (NLS: 640PKLKRQ646) of CUL5 (e.g., K642G/K644G mutations) significantly diminishes its nuclear translocation, impairing its ability to suppress cell proliferation ( CUL5 also suppresses endothelial cell proliferation and angiogenesis by promoting the degradation of Visfatin (NAMPT), thereby inhibiting MAPK/PI3K-AKT signaling (140)

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