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The effects of early life stress, postnatal diet modulation, and long-term western-style diet on later-life metabolic and cognitive outcomes

Initially, GLP-1 agonists were used mainly to lower blood sugar levels and hemoglobin A1c in diabetic patients

10.1016/S0896-6273(03)00065-5 Neuron 172 StickgoldR.WalkerM

While clinical trials have already established the weight loss benefits of GLP-1s, it is real-world evidence that will show whether these benefits translate into tangible system-level and socioeconomic gains, providing public payers and policymakers with a stronger basis on which to justify reimbursement