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doi: 10.1101/cshperspect.a020628 120 PisanuA.LeccaD.MulasG.WardasJ.SimbulaG.SpigaS.et al

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The dispute turns on whether Issue 2 is limited to gastroparesis, ileus, small bowel obstruction, and gallbladder injuries , or instead extends to additional alleged injuries including pancreatitis, malnutrition, micronutrient deficiencies, Wernickes encephalopathy, dehydration, acute kidney injury, aspiration, and related sequelae

This release of histamine and tryptase increases blood flow to the skeletal muscles during exercise.[ref] Hypoxia has also been shown to induce mast cell degranulation.[ref] This is a normal response for most people, and the body can handle a certain increase in histamine and tryptase