doi: 10.3390/nu12030605 25 ZhuBRenHXieFAnYWangYTanY
[20,21] Overview of Cancer Therapeutic Agents Chemotherapy agents can be divided into several categories: alkylating agents (e.g., cyclophosphamide, ifosfamide), antibiotics which affect nucleic acids (e.g., doxorubicin, bleomycin), platinum compounds (e.g., cisplatin), mitotic inhibitors (e.g., vincristine), antimetabolites (e.g., 5-fluorouracil), camptothecin derivatives (e.g., topotecan), biological response modifiers (e.g., interferon), and hormone therapies (e.g., tamoxifen).The agents most noted for creating cellular damage by initiating free radical oxidants are the alkylating agents, the tumor antibiotics, and the platinum compounds
BPC-157 is studied in preclinical literature for its multi-pathway signalling profile: VEGFR2AkteNOS activation, focal adhesion kinase signalling, growth-hormone-receptor upregulation, and nitric oxide system modulation
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