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Yes, if the pen was at room temperature (up to 86F/30C) for less than 21 days total and has not been used

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Docking substrates into the active site of the mutant Asn240Lys suffered from steric and entropic problems as Lys at position 240 oscillates (as evidenced by docking showing a wide range of different Lys240 positions), thereby obstructing access to the active site