The jump to 10mg may produce stronger GI effects than previous increases
Drinking kombucha (a fermented beverage containing probiotics) with a high-carb meal may blunt the rise in blood sugar after the meal, according to a recent study
This could act as a bridge when the medication is reduced or stopped
Further, although incompletely described, multiple studies are available to provide insights into the mechanistic underpinnings, which appear to be associated mostly with indirect cardioprotective benefits owing to the ability of GLP-1 RAs to address hyperglycaemia, and reduce body weight, and, amongst others, inflammation
These interactions have been proposed as a mechanism through which the peptide may influence gene expression programs associated with cellular senescence (Vanyushin et al., Biochemistry (Moscow), 2014)