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The NLRP3 (NOD-like receptor family pyrin domain containing 3) inflammasome is particularly relevant in the context of ethanol-induced neuroinflammation (De Filippis et al

superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), -glutamyltransferase (-GT), carnitine palmitoyltransferase 1 (CPT-1), lactate dehydrogenase (LDH), heme oxygenase-1 (HO-1), xanthine oxidase (XO)

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Drug Class: CNS Stimulant, Indirectly Acting Sympathomimetic Background Chemistry: Amphetamines are synthetic indirectly acting sympathomimetic agents that are structurally related to the naturally occurring stimulant ephedrine

This opposed the possibility that a generic response to D-HIS could explain the increased GSH level seen in the pGSH1-GAP1 strain with D-HIS