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Description

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R3TA provides a single pharmacological tool for studying the combined signalling consequences of simultaneous tri-receptor activation Pancreatic beta cell and insulin secretion models GLP-1 and GIP are the primary incretin hormones

Studies (75, 76) have shown that NOR can inhibit the destruction of bone and cartilage in AIA rats by reducing the expression of RANKL, IL-6, PGE2 and MMP-13 through the p38/ERK/AKT/AP-1 pathway