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While the major RCTs examining L-carnitine supplementation in the immediate post-MI setting showed no clinical benefit, a meta-analysis of L-carnitine intervention studies suggested its potential beneficial effect 54

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This is largely due to a shift in utilization toward brand-name and specialty drugs, including some newly approved high-cost cell and gene therapies. WellSense Health Plan (Massachusetts) However, the savings trend associated with generics is being eclipsed by another trend around the rising cost and utilization of specialty medications including biologicsSpecialty medications are used by approximately 2 percent of our members, but they account for more than 50 percent of total drug spend. Excellus Health Plan, Inc

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