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Caffeine is well-known for its ability to increase energy expenditure, enhance focus, and support endurance, making it a staple in fat burners
However, it is unclear whether NCOA4 can bind to the cell membrane before translocating to the cytoplasm, apart from the evidence demonstrating its truncated isoform SRC3s ability to bind to the cell membrane [44]
Adverse events occurred in 32% of patients at the 1,200 mg dose, including liver dysfunction in 8 patients with ALT elevations up to 311 IU/L
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