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In a recent study, tetracycline significantly reduced both LPS- and influenza-induced lung injury in mice by inhibiting inflammasome-caspase-1 dependent IL-1 and IL-18 production

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These maleimide functional groups play dual roles, that permitting a Toll-like receptor 2 binding peptide conjugation in order to improve cancer cell specific delivery, in the other hand, once in cytosol, maleimide efficiency improve oridonins redox imbalance promoting ability by simultaneous GSH depletion