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The report also highlights a "habit chaining" effect, with 76% of GLP-1 members reporting that one new habit leads to another, creating momentum over time

Changes range from acute inflammatory cell infiltrate(s) or occasional aggregates of lymphocytes/lymphohistiocytic cells/foci of mononuclear cells without associated alterations of adjacent hepatocytes, to large panlobular patches of distinct hepatocyte necrosis accompanied by polymorphonuclear and mononuclear (lymphocytes, plasma cells, macrophages) cellular infiltrates

In sensitivity analyses, see Table 3, GLP-1 RA use was associated with lower risk compared with SGLT-2 inhibitors among patients without a recent psychiatric history, but no difference was observed among patients with recent psychiatric history

Manton WI, Angle CR, Stanek KL, Reese YR, Kuehnemann TJ

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