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If you have had weight loss surgery and are experiencing fatigue or neurological symptoms, B12 testing and consultation with a qualified provider should be a priority

2023 Jul 21;29(27):4289-4316

Methionine helps synthesize glutathione, a natural antioxidant produced in the liver that helps eliminate toxins and speeds up fat removal within the liver, promoting liver function

Interestingly, exposure of endothelial cells to homocysteine would accelerate the rate of cellular senescence and increase the amount of telomere length lost per population doubling, through a redox-dependent pathway (Xu et al, 2000)

Because that figure comes from rodent research, many start patients at the low end (about 5 mcg/kg or a flat 250 mcg) and adjust over one to two weeks