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While the drugs have helped people lose substantial amounts of weight, potential side effects range from nausea, bloating, diarrhoea and fatigue, to more serious stomach, kidney and gallbladder problems and inflammation of the pancreas

Germline deletion of myostatin is viable and in several species shows a benefit not only in increased muscularity, but also in metabolic parameters 51,52

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dual agonists) resilience-focused biomarker panels machine-learning derived risk signatures trials that treat muscle health as a primary endpoint GLP-1RAs remain extraordinarily beneficial