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Tryptophan 32 mediates SOD1 toxicity in a in vivo motor neuron model of ALS and is a promising target for small molecule therapeutics

Journal of Cell Biology , 217 (11), 37963808

Studies have revealed that upon reaching the BBB, nanoparticles can cross via several mechanisms, including carrier-mediated, receptor-mediated, and adsorptive-mediated transcytosis, as well as passive diffusion, clathrin-mediated endocytosis, and micropinocytosis 59

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