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Gender: HR (Male) = 0.81

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In the studies of tirzepatide, for example, seniors on the drug were about twice as likely to stop taking their medication because of adverse events compared with younger adults and other older adults who were in the same study but got a placebo

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Initial appetite suppression often occurs before significant weight loss becomes visible on the scale

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There is currently no established evidence in UK regulatory documents that semaglutide alters thermoregulation , and reports of cold sensitivity are largely anecdotal

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GLP-1 controls appetite, stimulates glucose-dependent insulin release, suppresses glucagon, and slows gastric emptying, which is why it underpins weight-loss and diabetes drugs

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