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Cardiovascular issues: increased risk of heart disease due to high cholesterol levels (Ziga et al

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Patients may also choose to have their prescription sent to a local pharmacy through LSH, but pricing and availability can vary by pharmacy

Disease-specific evidence shows that patients with SSc complicated by ED often exhibit abnormal penile hemodynamics, including decreased peak systolic velocity (PSV), weakened flow-mediated dilation (FMD), and a decline in the cavernous artery Doppler index (55, 56), indicating that ED can be one of the manifestations of systemic vascular diseases