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Why Weight-Loss Drugs Tinker With Reward Circuits Glucagon-like peptide-1 (GLP-1) receptor agonists mimic a gut hormone that slows gastric emptying and tells the brain youre full. But the same receptors pepper the mesolimbic pathwaythe dopamine-rich circuit that makes whisky, cigarettes, and slot machines feel rewarding

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Many articles in this study indicated the patients included had adequately followed these guidelines, some indicating patients fasting well beyond the recommended guidelines, and still noted either increased residual gastric contents, aspiration events, or other GI-related symptoms in the perioperative setting (Santos et al

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