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Essential oil from seeds tested on HeLa, HepG2, MCF-7, Caco-2, and L929 cell lines (0.151 mg/mL) showed the highest cytotoxicity in HeLa, HepG2, and MCF-7 cells, suggesting a dose- and cell type-specific toxicity [170]

People who use it four to seven times per week have

further supported these findings by showing the upregulation of OXPHOS in invasive melanoma using a zebrafish tumor model [14]

doi: 10.1046/J.1365-2230.2003.01264.X 165 RajappaMChandrashekarLSundarIMunisamyMAnanthanarayananPHThappaDMet al