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Penicillin-based antibiotics (amoxicillin, penicillin V) and cephalosporins (cephalexin, ceftriaxone) generally maintain adequate absorption despite delayed gastric emptying, making them reasonable first-line choices for bacterial infections in patients using semaglutide

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However, the gastrointestinal side effects commonly associated with GLP-1 receptor agonistssuch as nausea, vomiting, and diarrhoeacan lead to dehydration and prerenal acute kidney injury, particularly in patients whose renal reserve is already limited

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Clinical Safety Standards for Telehealth GLP-1 Providers Evidence-based GLP-1 telehealth requires baseline cardiovascular screening, metabolic panel review, thyroid function testing, and assessment of personal or family history of medullary thyroid cancer