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The MTHFR enzyme is responsible for converting folate into its active form, 5-methyltetrahydrofolate

People who are generally healthy and who regularly eat animal products may not need to supplement at all

Its even more vital for pregnant or lactating women who are vegetarian/vegan to consume enough B12, as infants are at higher risk for B12 deficiency (7)

Additionally, if your gastrointestinal tract does not function normally, as with celiac disease or Crohns disease, you may have trouble absorbing or releasing vitamin B12, which will affect the levels in your body and how long the vitamin stays there

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