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However, in stressful, oxidative-compromising conditions, this reductase seems not to be sufficient, underlying the importance of this -glutamyl cycle (37)

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Proc Natl Acad Sci USA 90(15):72407244 Snchez-Pernaute R, Ferree A, Cooper O, Yu M, Brownell AL, Isacson O (2004) Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease