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Its often prescribed off-label for PCOS and weight loss

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20 There is one early blinded, placebo-controlled trial of NAC on its own in 43 patients with Alzheimers disease that found NAC, 50 mg per kg bodyweight (equivalent to 3750 mg for a person weighing 75 kg) per day for 6 months, to be superior to placebo in almost all outcome measures, although not all reached statistical significance

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While real-life experience can vary, heres what clinical trial results have found: Orforglipron : Phase 3 obesity trials in people without diabetes show up to 11% weight loss after 72 weeks when taking the highest dosage studied