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It concedes tirzepatide's numerical advantage in trial averages while arguing that potency on paper does not determine clinical success, because individual receptor sensitivity, tolerability and metabolic factors decide what actually happens

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In May, Canada became the first country in the G7 to approve a generic semaglutide injection, intended for type 2 diabetes patients but can be prescribed off-label for weight loss

However, IGF-IR overexpression is linked to autoimmune diseases like Graves disease

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