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The effects of midlife weight gain extend far beyond aesthetics, contributing to an increased risk of heart disease, type 2 diabetes (T2D), and other metabolic diseases

Moreover, we show that chitin biosynthesis is hormonally induced by ecdysteroid signaling

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Clinically, it alleviates GI disturbances and modulates the microbiota to suppress enteric pathogens ( Table 2 )

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