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PRP is an autologous blood fraction that contains a high concentration of platelets and their associated growth factors (GFs), including platelet-derived GF (PDGF), vascular endothelial GF (VEGF), transforming GF- (TGF- ), and epidermal GF (EGF) [6] (Fig

Among these, an indole derivative demonstrated a strong inhibitory effect on PHGDH (K d = 0.18 M) [12]

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