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In initial studies, a maximum tolerated dose (MTD) of 400 mg by mouth (PO) once daily (QD) was established in healthy subjects due to dose-limiting side effects such as nausea and vomiting (48)

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Participants with type 2 diabetes experienced slightly lower weight loss (19.7% versus 22.4% for non diabetic participants) but gained substantial metabolic benefits

Lifestyle Still Matters Lifestyle Still Matters Medication can help a lot, but lifestyle changes like eating healthy, moving your body, and getting good sleep hygiene are still key

Some think that a high-volume injection collapses some of the blood vessels, which also gets rid of their nerve endings, which means less pain in the tendon