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One of its principal targets is PARP, a nuclear enzyme involved in DNA repair and cellular stress responses

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What the Evidence Actually Shows This is the section to read slowly, because it is where the honesty lives

Glucagon-like peptide-1 (GLP-1)-based therapies, such as semaglutide and tirzepatide, have transformed obesity management, producing weight loss that narrows the gap with metabolic surgery at the same time as reducing the risk of obesity-related complications [2]