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A direct relationship between specific types of bacteria and GRP hydrolysis to ITCs was not established ( Metabolites of GRP produced by microbiota can be categorized into the following three groups: (i) GLs such as glucoerucin, (ii) ITCs such as SFN and erucin, and (iii) ITC-nitriles such as SFN-nitrile and erucin-nitrile