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Total body adiposity, triglycerides, and leg fat are independent risk factors for diabetic peripheral neuropathy in Chinese patients with type 2 diabetes mellitus

Biol Trace Elem Res 2014

Second, semaglutide activates GLP-1 receptors in the central nervous system, particularly in the brainstem area postrema and nucleus tractus solitarius, regions responsible for nausea and vomiting responses

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It is also investigated in models involving detoxification pathways and oxidative stress biology