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Ca 2+ acts as a key second messenger in regulating various physiological changes during capacitation, including hyperactivation of motility (Snchez-Crdenas et al., 2018), membrane fluidity alterations, and the activation of signaling cascades essential for the acrosome reaction (Buffone et al., 2014)

Future research should focus on unraveling the specific molecular mechanisms involved, which will enable the development of more effective, personalized dietary interventions that serve as adjunct therapies in comprehensive disease management

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doi: 10.3390/antiox13111355 163

Magnesium is involved in hundreds of enzymatic reactions including those that regulate calcium metabolism and bone mineral density