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Furthermore, the degree of kidney inflammation was found to decrease by 30%, the participants' blood pressure drop was as large as a blood pressure-lowering drug gives, and in them, a key measure of heart failure was reduced by 33%

has received grants or contracts from National Institutes of Health (NIH)/National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Jaeb Center for Health Research, and Medtronic

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The authors determined that the evidence base is not yet sufficient to draw firm positive or negative conclusions, and that significantly more research is needed before clinicians can feel confident in either direction

Retatrutide 8 mg roughly matches this, and the 12 mg dose exceeds it