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S., et al., Overexpression of Human Selenoprotein M Differentially Regulated the Concentrations of Antioxidants and H 2 O 2 , the Activity of Antioxidant Enzymes, and the Composition of White Blood Cells in a Transgenic Rat, International Journal of Molecular Medicine 21 (2008): 169179

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Duration: Long-term use may be needed to maintain results, as visceral fat can return after discontinuation

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Moreover, a pilot study in 19 healthy adults suggested that the bioavailability of R, S -lipoic acid and R -lipoic acid may vary with age and gender (13)