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The article says that unlike some injectables, oral liquid formulations show measurable absorption reduction when taken with high-fat meals, which is why the guidance it describes favors an empty stomach or light, low-fat food

In long course of HT mainly IgG4 autoantibodies are produced (91), which trigger the development of IgG4-related disease (IgG4-RD)

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This approach significantly reduces gastrointestinal side effects, which are the most common adverse reactions to these medications

However, research shows that for many people, lifestyle changes alone are not enough to prevent rebound weight gain completely