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Some users notice changes in physical comfort and recovery quality before that

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The bottom line is that we needed replication of these ndings with additional studies to answer these and other questions

Similarly, a study based on swimming exercise for a total of four hours showed an increase in NAD + levels, yet also in this case, no measurements of mitochondrial function were performed 309 , reinforcing the need for more exercise-based investigations to further define how NAD + and mitochondrial homeostasis are perturbed and connected during exercise

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