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However, research shows that it due to the short half-life of this medication which can be between 2 to 10 minutes (vs 36 hours for hCG), injections a minimum of 6 times daily are needed have a similar clinical effect as two 500iu injections of hCG Once taken, a single dose may be in a patients system and effective from anywhere between 36-72 hours depending on the individual patient, their reaction to the medication and the dose/amount of medication taken