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In another study, Li et al

Research on the management of NAFLD is an imperative need due to its high prevalence, morbidity, and mortality and the concomitant lack of any specifically approved medication

The most recent of these studies was published in 2006

In conclusion, most animal studies support a beneficial effect of GLP-1RAs on NAFLD histology, including steatosis and inflammation, but not on fibrosis, while a few initial animal studies with GLP-1RA related polypeptides have provided limited evidence for a more favorable effect of peptide polyagonists on hepatic fibrosis

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